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Compounded medications provide for customization of strengths and volumes, as determined necessary by the prescribing physician for the identified patient, that may not be available in commercial products

If a '50mg' vial actually contains 53mg and you add 2mL bacteriostatic water, your true concentration is 53 2 = 26.5mg/mL

Doing this will give you a better idea of the severity of a B12 deficiency (if there is one) and how much B12 you should be taking on the reg

And, you guessed it, melatonin production declines with age

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The key is consistency within your rotation pattern