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TB-500 in actin polymerization (= reorganization of the cellular skeleton) and mobilization of stem cells to the site of injury

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Treatment of hMSC with 300 nM Ex-4 for 7 days upregulated leptin and its receptor in both undifferentiated and osteogenically induced cells

Ahmann AJ, Capehorn M, Charpentier G et al (2018) Efficacy and safety of once-weekly semaglutide versus exenatide ER in subjects with type 2 diabetes (SUSTAIN 3): a 56-week, open-label, randomized clinical trial

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This medication is a delicate peptide that can degrade if not kept under the right conditions