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[23] In two clinical trials, hypothyroid patients who took selenium showed reduced thyroid antibodies compared to a placebo [24] and improved ultrasound findings

PMCID: PMC6033032

Given the early stages of this therapeutic approach senescence therapeutics will need to overcome challenges related to biomarker identification, target engagement, CNS penetrance and safety

Gonzalez-Alvarez J, Sos-Pena R

First, they come from different populations and trial designs than the cagrilintide studies SURPASS-2 compared tirzepatide with semaglutide in diabetes

The cells were washed three times with pre-warmed Hanks Balanced Salt Solution (HBSS) (Gibco) (200 L/well) and starved for 1 h in HBSS (250 L/well)