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A double-blind, randomized trial of 151 patients with ovarian cancer found that intravenous glutathione therapy reduced the toxicity of cisplatin and improved quality of life

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While the berberine treatments caused more gastrointestinal side effects, it also yielded a hypoglycemic effect tied to the inhibition of a specific gut microbe: Ruminococcus bromii, which may be responsible for the underlying antidiabetic effect of berberine