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12 Exendin (9-39), a GLP-1 receptor antagonist, and blockade of dipeptidyl peptidase-4 (DPP4), an enzyme responsible for GLP-1 degradation, did not nullify the decreased alcohol consumption and alcohol-seeking behaviors induced by liraglutide and semaglutide, signifying the lasting impact of the GLP-1 receptor agonists despite antagonistic influences

Wegovy is approved for weight management and reducing the risk of heart attacks and strokes, while metformin is approved for Type 2 diabetes

They should not be used to self-prescribe, self-adjust dosing, or replace instructions from a licensed provider or pharmacy

Body composition at this point has shifted meaningfully

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