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Pathophysiology of NAION It is presumed to result from a circulatory insufficiency, or infarct, within the retrolaminar portion of the optic nerve head that is supplied by the short posterior ciliary arteries (SPCA)

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7 Over 55% of the weighting in this meta-analysis was contributed by the LOOK AHEAD trial, which assessed whether intensive lifestyle interventions for weight loss would reduce cardiovascular morbidity and mortality in individuals with overweight or obesity and type 2 diabetes (T2DM)