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Redox Biol 75:103256 Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S et al (2013) Wilsons disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease

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The biosynthetic incorporation of these PUFAs into phospholipids requires two key enzymes: acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3)