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13b, Supplementary Table 9), indicating that the interactions between the C-terminal tyrosine and RAMP3 can compensate, in this peptide context, the reduced CTR ECD affinity derived from the P37Y substitution
Its side effect profile is essentially invisible
Could theoretically amplify tricyclic side effects (orthostatic hypotension, anticholinergic burden) beyond tolerable thresholds
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In addition to breaking down fats and carbs for energy, its responsible for the production of sex and stress-related hormones including testosterone
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