l-cysteine vs l-glutathione Effects of the Usage of (l-Cys) on Human Health Extracellular and intracellular l-cysteine/l-cystine balance

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Analogously, in the context of OA, it is speculated that local ferroptosis in joints may release metabolites such as pro-inflammatory factors and LPO into the bloodstream, thereby regulating the compositional and structural features of the gut microbiota

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These cells subsequently induce the production of IL-22, which regulates the release of antimicrobial peptides and enhances their expression in the gut epithelium, thereby reducing pathogen infectivity by sequestering metal ions [52]

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