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Diabetic patients with peripheral neuropathy have significantly worse everyday functioning and well-being, according to a pilot study assessing the effect of DPN on quality of life (98)

To optimize the bioavailability of systemically targeted inhaled drugs with favourable aerodynamic properties, dry powder aerosols have been engineered as large porous particles, thereby simplifying inhaler design 103,104,105

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Because it clears from the system rapidly, maintaining a steady-state blood plasma concentration requires dailyor preferably twice dailysubcutaneous administration to maximize the continuous healing window