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Chronic daily administration of an amylin receptor or GLP-1R analog as a mono- or combinatorial-therapy on body weight gain and food intake Experiments were designed to determine whether chronic combinatorial administration of an amylin receptor agonist with a GLP-1R agonist is superior in producing a greater magnitude of sustained weight loss and food intake suppression compared to monotherapy in a diet induced obese rat model

Nanoscale 8 , 1735017356 (2016)

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however, the processes involving GLP-1R activation, atherosclerotic reduction, and enhanced blood flow are unclear

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