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Over time, the darker, pigmented cells on the surface are shed away, and the newer, more even-toned cells take their place

Notably, tumor cells exhibit aerobic glycolysis (the Warburg effect), a metabolic reprogramming wherein glycolysis dominates ATP production despite oxygen availability, rapidly generating ATP and lactate to fuel neoplastic proliferation (15)

7T proton magnetic resonance spectroscopy of gamma-aminobutyric acid, glutamate, and glutamine reveals altered concentrations in patients with schizophrenia and healthy siblings

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