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However, the initial intent was never to use these molecules for cosmetic or aesthetic purposes
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Wimmelmann CL, Dela F, Mortensen EL
doi: 10.1186/s13048-025-01621-6
In WEGOVY clinical trials in adults for weight reduction, severe gastrointestinal adverse reactions were reported more frequently among patients receiving WEGOVY (4.1%) than placebo (0.9%)
Further, homozygous MTHFR 677TT appeared to be synergistic with heterozygous mutations of coagulation factors Factor V or prothrombin for the development of deep venous thrombosis or pulmonary embolisms
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