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The activation of PPAR, therefore, maintains IS and exhibits an anti-inflammatory function, whereas IR causes impaired adipogenesis and increased risk of T2DM [44, 45]

Enhanced autophagic activity may contribute to the preservation of neuronal function by improving cholinergic signaling and reducing oxidative stress accumulation

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The relative cellular MDA concentration was presented as a percentage of control after normalized to protein contents

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Avoiding very low-calorie diets is essential, as severe caloric restriction can actually slow metabolic rate as the body adapts to conserve energy