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doi: 10.2967/jnumed.111.088922

Presence of the knockout alleles of Epac1/2 in the tumor tissues was confirmed by genotyping (Fig

In particular, previous studies have reported and alternative splicing of sequences encoding a region of eight amino acids in repeat 15 of FLNA, and an internal deletion of 41 amino acids between repeats 19 and 20 (residues 21272167) that identify FLNA variant-1 (77) that is widely expressed at low levels (70)

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Collectively, these findings suggest that metformin may alleviate H 2 O 2 -induced oxidative damage, ameliorate chondrocyte apoptosis, and protect against ECM degeneration

Lancet 2003