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Cellular experiments further confirmed that the L-OPA1/S-OPA1 ratio and Irisin/FNDC5 expression were significantly upregulated in 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR)-treated cardiomyocytes, which significantly increased PINK1/Parkin, SOD2 expression, and LC3II/I ratio, decreased p62 expression, and increased mitophagy and antioxidant capacity in AICAR-treated cardiomyocytes (Li H

Mitochondrial dysfunction and oxidative stress in Alzheimer's diseasea step towards mitochondria based therapeutic strategies

Neuroprotection Brain health: Glutathione helps protect the brain from oxidative stress, potentially benefiting conditions like Parkinson's disease, Alzheimers, and other neurodegenerative disorders

Hepato(geno)toxicity assessment of nanoparticles in a HepG2 liver spheroid model

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