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The ascitic fluid contains growth factors secreted by both cancer and stromal cells 9 and these factors are mitogenic to cancer cells, contributing for an ideal microenvironment for tumour growth 10,11

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Il-1 : ** P = 0.0062), endotoxin-mediated inflammation ( Tlr4 : *** P = 0.0002), lipid metabolism ( Pparg : ** P = 0.0099) and fibrosis ( Col11 : * P = 0.0372) significantly differed between the RM-LNC group and the CTRL WDF group (Supplementary Information Fig