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The initiation phase involves the generation of ROS, including free radicals like hydroxyl radicals (OH), superoxide anions (O 2 ), and non-radical oxidants like hydrogen peroxide (H 2 O 2 ) [48, 49]

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This is consistent with our results, as cisplatin doesnt seem to trigger ferroptosis in NB, and with the concept of drug-tolerant persister cells that are induced by cisplatin in NB 82 and exhibit a transition toward a MES-like cell state 12,13

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GLP-1s also act on areas of the brain that control nausea, so youre getting signals from both the gut and the brain at once

Im seeing improvements not just in weight or glucose, but in inflammation-related symptoms. Reporting on what they have seen in clinics, they said, Patients are reporting less pain, fewer flares, and improved energy