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Diets rich in fiber, antioxidants, and anti-inflammatory nutrients, such as the Mediterranean diet, favor beneficial microbial communities, while high-fat, high-sugar diets exacerbate dysbiosis and inflammation (Vinelli et al., 2022
Specialist supplements such as DHEA, high-dose myo-inositol, or NAC may be appropriate, but should be discussed with a clinician particularly DHEA, which is only indicated for diminished ovarian reserve
There were inhibited mRNA of inflammatory mediators (iNOS, IL-6, IFN and TNF-), increased expression of HSP 70 and 90, and antioxidant proteins, such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2 and GST-pi [30]
The specificity of our results can be placed into perspective by comparison to other studies of cerebrospinal fluid
In some embodiments, the otic formulation or composition comprises about 0.3% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof