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Nanoparticle systems, including liposomes, polymeric nanoparticles, and solid lipid nanoparticles, could improve peptide stability but suffered from batch-to-batch variability, limited scalability, and absorption efficiencies that rarely exceeded 5% in human studies

Endogenous tryptophan metabolite 5-Methoxytryptophan inhibits pulmonary fibrosis by downregulating the TGF-beta/SMAD3 and PI3K/AKT signaling pathway

All participants gave written informed consent and this part of the study was approved by the local ethics committee of Ludwig-Maximilians University of Munich, Germany (333-10) and carried out in accordance with the approved guidelines

Chin Med J 2021