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Stiles LI, Ferrao K, Mehta KJ

FDA-Approved Uses in the USA In the United States, semaglutide is marketed under three main brand names, each approved for specific conditions: Wegovy: Specifically FDA-approved for chronic weight management in adults with obesity or overweight individuals with at least one weight-related condition (like high blood pressure)

Once the original manufacturer can keep up with the demand, compounding pharmacies are only allowed to make the drug in specific circumstances

Both formulations work through the same GLP-1 receptor mechanism, so both can produce similar heart rate effectsthough individual responses depend partly on genetics and dose titration speed

Extend the monitoring interval to weekly liver enzyme checks for the first 4 weeks