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Comparing oral and intramuscular vitamin B12, a 2005 Cochrane Review revised in 2018 revealed that large doses of oral vitamin B12 might be equally effective as intramuscular delivery in achieving short-term hematological and neurological responses in vitamin B12-deficient individuals

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It means the evidence base is thin, and expectations should be calibrated accordingly

Research suggests oral B12 supplements (especially sublingual forms) can be just as effective as injections for treating deficiency

Over the years, weve dedicated more than 1,000 cumulative hours to researching therapeutic peptides