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Emanating from Paneth cells, sPLA2-IIA acts as an antimicrobial agent, shaping the gut microbial landscape

It modulates inflammatory and apoptotic markers, enhances antioxidant defenses, and suppresses JNK/p-PERK and Caspase-12 signaling

SULT1A1 is predominantly expressed in the liver (Hempel et al., 2007)

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however, it has certain limitations in terms of side effects and a limited therapeutic window ( As a continuation to researches concerned with natural compounds, phytic acid (PA) was evaluated in this study in APAP induced hepatoxicity based on its antioxidant properties and its ability to modulate iron metabolism