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TD Cowen analyst Steve Scala has flagged the high rate of discontinuation as a concern and suggested it could make outcomes of future trials harder to predict

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This paper examines the economic implications of GLP-1 medications, focusing on pricing strategies, disparities in access, and their broader impact on the healthcare system

Good practice for all reconstituted vials includes: Labelling each vial with the date and time of reconstitution, the diluent used, the concentration, the assigned beyond-use date (as per sponsor/manufacturer data), and the initials of the person who prepared it

Counteraction of GLP-1 effect on gastric emptying by co-infusion with prokinetic drug erythromycin during a liquid test meal diminished GLP-1s ability to decrease postprandial hyperglycemia in patients with T2DM (153)