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Rapid fat loss leads to loose or stretching skin, which increases irritation and dryness

Stimulates insulin release and reduces liver glucose production for better glycemic control while curbing appetite and supporting your body's use of stored fat for energy

Nausea or diarrhea can cause dehydration, which can stress kidney pathways

Supplemental glutathione has been shown to lower acetaldehyde levels in the body, though individual symptom relief can vary

Ensuring good sleep hygiene and addressing any underlying sleep issues is essential for reducing headache frequency

doi:10.1016/j.ajcnut.2025.04.023 2 DiNicolantonio JJ, Berger A