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Against hypoglycemic seizures from insulin overdose, BPC-157 prevented brain lesions in cerebral cortex and hippocampus while simultaneously protecting the gut and liver, demonstrating unified cytoprotection

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Dietary intake of vitamin C has been shown to have protective effects in patients with MASLD and MASH

Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson A, Cooper MA, Gro O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB

Pioglitazone inhibits diabetes-induced atrial mitochondrial oxidative stress and improves mitochondrial biogenesis, dynamics, and function through the PPAR-/PGC-1 signaling pathway