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Most side effects were temporary and resolved during treatment

Supervision required : Texas (mandatory physician oversight with prescriptive authority agreements one MD can delegate to max 7 NPs), Pennsylvania (no independent NP practice yet), Florida (limited autonomy for primary care NPs, but psychiatric NPs generally need physician partnership)

Dysesthesia is abnormal touch sensation tingling, numbness, or unusual skin sensitivity reported in 12.520.9% of retatrutide patients at 12mg (varying by trial population), versus less than 1% with tirzepatide or semaglutide

In a 12-week clinical trial, participants lost weight and saw a reduction in waist/hips measurements

Fan, Y., & Pedersen, O