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The antioxidant properties of lipoic acid come from its ability to directly scavenge ROS, its metal-chelating activity, and its potential to react with and promote regeneration of other antioxidants such as glutathione and vitamins E and C

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Subcutaneous formalin and intraplantar carrageenan increase nitric oxide release as measured by in vivo voltammetry in the spinal cord

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Glutathione has been explored as a treatment for melasma due to its antioxidant and skin-lightening properties