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Creation of Super HGF: When HGF is treated with lipoic acid trisulfide (LASSS) at an 1:8000 molar ratio, its binding affinity for c-met increases more than two-fold compared to unnitrated, native HGF while remaining highly resistant to nitration

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Notably, the lignan composition showed no significant variation across extracts obtained with different oils

Gorski D (2011)