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Additionally, while rare, high doses of B12 can sometimes cause a temporary drop in potassium levels (hypokalemia) as the body ramps up the production of new red blood cells

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Skin Sensitivity or Rash Some patients notice irritation, redness, or a mild rash around the injection site

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Indeed, Pink1-KO mice, a model that is typically asymptomatic of PD and void of dopaminergic degeneration, exhibited a pronounced reduction in the density of tyrosine hydroxylase-positive neurons in the dorsal and ventral striatum and dopamine transporters following infection by a pathogenic Gram-negative bacterium, Citrobacter rodentium (Matheoud et al., 2019)