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Further clinical research is needed to fully understand the potential applications of crocin in human health

Those in smaller centers or rural areas may need to rely on home-based cold water immersion or ice application rather than professional chambers

DOH entities already have active initiatives aligned with Domain 4 projects, so PPS should look to join in these efforts

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Martin S, Giannone G, Andriantsitohaina R, Martinez MC (2003) Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis

"It's a great option for somebody who is pregnant because both of those ingredients, at this strength, are safe in a setting of pregnancy." It's also a good pick for individuals with melasma, another type of hyperpigmentation, she said