While their mechanisms of action are similar, topical acetyl hexapeptide-8 does demonstrate a lower efficacy than injected Botox, but as researchers note this is to be expected.22 Similar results were found in a small 2013 study, with the total anti-wrinkle efficacy of the Argireline treatment group being 48.9% compared to 0% in the placebo group.23 However, a more recent 2023 study investigating the effects of serum containing Argireline and hyaluronic acid found the results to be not statistically significant.24 This means that more research is needed before claims that Argireline is a true alternative to Botox can be confirmed or denied
Reduced shedding, slightly improved hair texture, or the appearance of fine vellus hairs are early indicators that the protocol is engaging follicle biology
Dihexa (N-hexanoic-Tyr-Ile-(6)-amino hexanoic amide) is an oral active, bloodbrain barrier-permeable angiotensin IV analogue
A prescription is required when applicable to the formulation and treatment plan
Fendrich V, Oh E, Bang S, Karikari C, Ottenhof N, Bisht S, et al
cerevisiae W303-1b cells were transformed with the linearized recombinant plasmids to obtain engineered strains W303-1b/F/GAP, W303-1b/F/GAP, W303-1b/F/GAL1 and W303-1b/F/PGK1
