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There is no general biochemical reason that every patient must avoid using them during the same treatment period

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After a 30-min stabilization incubation, PBS (without IBMX) and 100 M 3-isobutyl-1-methylxanthine (with IBMX) (Sigma Chemicals, St Louis Mo) was added and incubated for 60 min so that each rat served as its own control

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Panel 1 (Pharmacological Foundations): illustrates atropines chemical structure and plant origin, emphasizing its high affinity for muscarinic receptors as a tertiary amine capable of central and peripheral effects

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