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STEP-HFpEF Trial (NEJM, 2023): 13.3% weight loss plus major improvements in HFpEF symptoms and function

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Others reported that only about 17% of patients show a positive inotropic effect to GLP-1 stimulation in the ventricle, and no response to glucagon receptor stimulation and no studies on GIP receptors stimulation in the human ventricle are available (Neumann et al

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