Numerous additional early deleterious effects on cardiac structure and function have been reported in T2DM, including smaller cardiac chamber volumes, impaired myocardial energy utilisation, coronary microvascular dysfunction, myocardial steatosis, focal and diffuse fibrosis, and dysregulated myocardial calcium handling, 96,97 that are not included in the current classification of Stage B HF or detectable with echocardiography
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Liraglutide and the Risk of Acute Gallbladder or Biliary Disease in Patients With Type 2 Diabetes: Nissen, S
(2.1) The recommended starting dose in patients not currently treated with metformin is 100 mg sitagliptin and 1000 mg metformin HCl once daily, with gradual dose escalation recommended to reduce the gastrointestinal effects due to metformin
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