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The diabetes rate has also remained flat for the past few years, according to Gallups data

10.1016/j.bbamcr.2019.118535 Biochim Biophys Acta Mol Cell Res

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To what extent have those margins been compressed

Whilst inclusion of more chemicals with antagonistic activity would be desirable for mechanistic understanding and complete characterisation of a chemicals activity towards the respective receptor, such information was scarce, and support from human health-relevant studies (i.e., human in vivo information) was lacking

Svensson, E