But its important to know that celiac is distinct from those conditions, including gluten intolerance and a wheat allergy, because it's an autoimmune disease in which the immune system attacks the small intestine, leading to malabsorption
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Several factors compound the indirect pathways described above, creating significantly higher vulnerability in certain populations
They induce the expression of inflammation-related genes, including CCL2 and CCL7, which enhance macrophage recruitment and chemotaxis (105)
low ROS levels have a positive impact of cell proliferation and survival and cellular adaptation to stress necessary for tumour progression [5,6,7]
This can be explained by looking into the basic molecular mechanisms involved: a high NADPH/NADP + ratio within beta cells facilitates the coupling of glucose stimulus with insulin release, as demonstrated by the increased insulin secretion in knock-out mice for NOX2 [110]
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