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We discuss classical and novel strategies to address the existing challenges in the field, presenting a state-of-the-art overview that advances the understanding and potential application of exosome-based nanomedicine in cancer therapy

The optimal number of BMSCs for intradiscal delivery (4 weeks after NP aspiration) was estimated in Beagles, based on the survival rate and apoptosis of CLCs in BMSC-injected IVDs [26]

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Int J Mol Sci 18(4):725