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Hegde VL, Nagarkatti PS, Nagarkatti M

The visual impact is dramatic for both, though the absolute number differs

Clinically this is how athletes present when they have "REDs", or relative energy deficiency in sport

While most people tolerate them well, its helpful to know what side effects to expect, especially in the first few weeks of treatment: nausea vomiting diarrhea constipation headaches fatigue These symptoms are well-documented across clinical trials and often appear during the dose escalation phase

The needle can be perfect and the dose can be exact, but poor injection mechanics still cause pain, bleeding, and suboptimal medication delivery

If weight loss as stalled - despite diet, exercise, or medications - the problem is usually metabolic signaling, not effort