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1 Introduction Characterized by cyclical inflammatory manifestations throughout distinct regions of the gastrointestinal tract, the clinical spectrum of inflammatory bowel disease (IBD) encompasses ulcerative colitis (UC) and Crohns disease (CD)

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They are awaiting grant of a patent by the US Food and Drug Administration to be used for the treatment of melasma, freckles, lentigines and postinflammatory hyperpigmentation

Initially, the pain may be mild and unnoticed

Elimination of acetaminophen is principally by liver metabolism (conjugation) and subsequent renal excretion of metabolites

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