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While no single method emerged as superior of all the compounds evaluated, multiple approaches exhibit a higher value

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Clinical data from a study involving 110 ischemic stroke patients showed that treatment with Semax at 6,000 mcg daily for 10 days significantly increased plasma BDNF levels, and these elevated levels correlated with improved functional outcomes

From an implementation standpoint, the standardized liquid formulation enables rapid local absorption with minimal systemic exposure and ensures uniform mucosal coverage, consistent dosing, and prolonged mucosal contact, features likely to reduce the formulation heterogeneity that has hampered prior topical studies and to enhance adherence 21