This feature renders cancer cells more sensitive to external stimuli that further increase the production of ROS 145,146,147 , and, as schematically summarized in Table 1, an increasing number of therapeutic strategies are being developed to elevate ROS levels to overwhelm the redox adaptation of the same cells, inducing oxidative stress incompatible with cellular life 148,149,150,151 (Fig
Jikah & Edo provide a comprehensive overview of M
Relative mRNA levels were determined using qPCR with the iTaq Universal SYBR Green Supermix (Bio-Rad Laboratories)
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GLP-1RA has been placed prominently in the international recommendations for the treatment of T2D as the first injectable agent before insulin due to the advantageous outcomes in cardiovascular safety studies that demonstrated a reduction of the combined cardiovascular endpoint three-component major adverse cardiovascular event (MACE-3
