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Therapeutic Research Protocol Dose: 0.3 0.5 mg (= 1220 clicks) Duration: 3 5 weeks Frequency: Daily, evening administration Cycle Interval: 3 4 weeks off before repeating Goal / Description: Higher-dose model for stress-response and neuroendocrine regulation studies

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MD and docking studies reveal that the functional switch of CYFIP1 is mediated by a butterfly-like motion