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Enter the dynamic duo of Semaglutide and Tirzepatide

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GLP-1 receptor agonists are medicines that mimic a natural hormone in our body called GLP-1 (glucagon-like peptide-1)

When you take semaglutide GLP-1, it signals your brain to feel fuller faster and reduces hunger, which naturally leads to eating fewer calories

The article dates the hormone's identification to 1987, when researchers were studying intestinal hormones and its role in post-meal glucose regulation, and dates the first synthetic GLP-1 receptor agonist, exenatide, to FDA approval for type 2 diabetes in 2005

GLP-1R agonists reach reward circuits, hinting at use in substance disorders