After protein extraction, Filter-Aided Sample Preparation (FASP) was used for digestion
As for cardiac muscle, a special kind of striated muscle, previous reports demonstrated that the mechanisms of SAMS in cardiac muscle mainly concentrate on mitochondrial dysfunction and apoptosis (Bonifacio et al., 2016
A total of 1,197 patients were randomized in a 2:1 ratio to receive semaglutide 2.4 mg subcutaneously once weekly or placebo for 240 weeks
The disease is characterized by progressive glandular hypoplasia, invasion of the affected lacrimal and salivary glands by CD4 + T cells, along the existence of anti-Ro/SSA antibodies in the serum [275, 276]
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10.1186/s12951-025-03104-8 J