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This combined burden of obesity and malnutrition is associated with significant risks including exacerbation of comorbid disease, increased risk of sarcopenic obesity, immune dysfunction, delayed wound healing, anemia, metabolic disturbances and impaired mood and cognition [63,64]
These results are particularly notable because they demonstrate that retatrutide's weight loss translates into meaningful clinical improvements, in this case, significant pain reduction for people with obesity-related joint problems
Ayyad C, Andersen T
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A phase III randomized trial (NCT04211337) compared first-line selpercatinib with physicians choice of cabozantinib or vandetanib (control group)