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These recommendations do not replace clinical judgement and are due for review in December of 2024

However, these trials were not specifically designed to assess bone density changes or fracture risk as primary outcomes

The final approved dosing, if and when retatrutide receives FDA approval, will be determined by the regulatory review process and may differ from the trial protocols

Patients who pick 8 PM Thursdays and stick to it outperform those who chase 'optimal' timing by shifting between mornings, afternoons, and evenings based on daily convenience

This might suggest that tirzepatide affects the gut microbiota [81]

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