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The method of embodiment 18, wherein the thiol or a derivative thereof is D-methionine

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Typical deficiency symptoms include fatigue, xerophthalmia, impaired night vision, dry skin and hair, a weakened immune system, and infertility ( Cancer patients often have subclinical vitamin A deficiency

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Selenium, a trace element highly concentrated in the thyroid gland, is essential for the activity of several selenoproteins involved in antioxidant defence and thyroid hormone metabolism

If CKD is the documented cause, D63.1 applies with the N18.x code sequenced first