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Aspartate transaminase (AST) and ALT values are usually normal, although in immense overdose, elevated values can be detected in as little as 812 hours

[67] studied a cohort of over 400,000 T2DM patients above the age of 65 and found that DPP-4i were associated with a 21% decrease in the risk of MACEs (including myocardial infarction and ischemic stroke) with a 46% overall decrease in risk of all-cause mortality

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Pros: Free from parabens and approved by the FDA for safety