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Gastrointestinal adverse effects are the most common reason patients discontinue Orlistat

9 Manchikanti L, Buenaventura RM, Manchikanti KN, et al

The rats were euthanized, and tissue samples (brain, heart, kidneys, liver, spleen, lung, stomach, intestine, muscle, grease, ovaries, womb, testicles, and thymus) were collected at 3 min, 10 min, 1 h, and 24 h after administration (three males and three females at each time point)

Occupations requiring repetitive arm movementsplumbers, painters, carpenters, butchers, and office workersare commonly affected

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This underscores the importance of not only monitoring alcohol intake but also ensuring proper hydration when drinking